SCHEMBL353890

SCHEMBL353890

Cc1nc2ccccc2n1C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.63
KDM4E B2RXH2 8/20 0.62
ALDH1A1 P00352 7/20 0.62
LMNA P02545 3/20 0.62
ATM Q13315 1/20 0.59
HTT P42858 2/20 0.57
MAPK1 P28482 2/20 0.57
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
RAB9A P51151 4/20 0.55
NPC1 O15118 3/20 0.55
TP53 P04637 3/20 0.55
HSD17B10 Q99714 3/20 0.55
GAA P10253 2/20 0.55
PKM P14618 2/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.53
MAPT P10636 3/20 0.53
HPGD P15428 2/20 0.53
TNF P01375 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL19182582 0.98 SMN1; SMN2 (0.61) SMN1; SMN2KDM4EALDH1A1LMNAATM
Bromide SCHEMBL5318089 0.98 SMN1; SMN2 (0.61) SMN1; SMN2KDM4EALDH1A1LMNAATM
Iodide SCHEMBL336206 0.98 SMN1; SMN2 (0.61) SMN1; SMN2KDM4EALDH1A1LMNAATM
Iodide SCHEMBL336205 0.98 SMN1; SMN2 (0.61) SMN1; SMN2KDM4EALDH1A1LMNAATM
Hydrochloric Acid SCHEMBL20291495 0.96 SMN1; SMN2 (0.59) SMN1; SMN2KDM4EALDH1A1LMNAATM
Formamide SCHEMBL17938372 0.89 SMN1; SMN2 (0.52) SMN1; SMN2KDM4EALDH1A1LMNAATM
SCHEMBL1171430 0.84 MEN1 (0.69) SMN1; SMN2KDM4EALDH1A1LMNAATM
SCHEMBL29354143 0.84 ALDH1A1 (0.50) SMN1; SMN2KDM4EALDH1A1LMNAATM
SCHEMBL18431639 0.83 ALDH1A1 (0.65) SMN1; SMN2KDM4EALDH1A1LMNAATM
SCHEMBL22636409 0.82 KMT2A (0.45) SMN1; SMN2KDM4EALDH1A1LMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2006 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344630-B2 Novel, heavy vitamin B12 derivatives CHARLES STURT UNIVERSITY (AU) 2025-07-01 US claimed
US-20240368659-A1 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS BIOSYNTIA APS (DK) 2024-11-07 US claimed
CN-118079660-A Preparation method and application of zeolite-imidazole ester framework material film 中国科学院大连化学物理研究所 2024-05-28 CN claimed
EP-4370653-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS Biosyntia ApS (DK) 2024-05-22 EP claimed
US-20240101591-A1 NOVEL, HEAVY VITAMIN B12 DERIVATIVES CHARLES STURT UNIVERSITY (AU) 2024-03-28 US claimed
US-11939225-B2 Highly siliceous form of zeolite RHO ExxonMobil Technology and Engineering Company (US) 2024-03-26 US claimed
EP-4331561-A1 USE OF ORAL CARE COMPOSITION Unilever IP Holdings B.V. (NL) 2024-03-06 EP claimed
CN-117524740-A 3D printing zinc vanadate/carbon nano composite electrode and preparation method and application thereof 中国科学院福建物质结构研究所 2024-02-06 CN claimed
US-11884695-B2 Heavy vitamin B12 derivatives CHARLES STURT UNIVERSITY (AU) 2024-01-30 US claimed
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
WO-1999020608-A1 ISOQUINOLINES AS UROKINASE INHIBITORS PFIZER LIMITED (GB) 1999-04-29 WO claimed
EP-0906430-A1 BIOSYNTHESIS METHOD ENABLING THE PREPARATION OF COBALAMINS Aventis Pharma S.A. (FR) 1999-04-07 EP claimed
WO-1997043421-A1 BIOSYNTHESIS METHOD ENABLING THE PREPARATION OF COBALAMINS RHONE-POULENC RORER S.A. (FR) 1997-11-20 WO claimed
EP-0318294-B1 Dimeric and trimeric cationic dyes NIPPON CHEMICAL WORKS (JP) 1994-12-28 EP claimed
CN-1054799-A The relevant polypeptide of biosynthesizing cobalami and/or cobamide, dna sequence dna, its preparation method and the application of these polypeptide of encoding RHONE POULENC BIOCHIMIE (FR) 1991-09-25 CN claimed
US-4889911-A ESTERIFICATION, ESTER INTERCHANGE; CATALYSIS WITH HETEROCYCLIC NITROGEN COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1989-12-26 US claimed
EP-0318294-A2 Dimeric and trimeric cationic dyes NIPPON CHEMICAL WORKS CO., LTD (JP) 1989-05-31 EP claimed
EP-0303931-A2 Process for the fabrication of thermotropic, wholly aromatic polyesters and polyestercarbonates BAYER AG (DE) 1989-02-22 EP claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed
US-4542394-A MULTILAYER-DIAZONIUM LAYER AND COUPLER LAYER CONTAINING BENZIMIDAZOLE COMPOUND RICOH COMPANY, LTD. (JP) 1985-09-17 US claimed