Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 10/20 | 0.48 |
| ▸ | GRM5 | P41594 | 9/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21750805 | 0.89 | GRM1 (0.46) | GRM1GRM5NAMPTJAK2JAK3 | |
| SCHEMBL31379895 | 0.87 | GRM1 (0.48) | GRM1GRM5NAMPTJAK2JAK3 | |
| SCHEMBL31379880 | 0.83 | JAK2 (0.56) | NAMPTJAK2JAK3PTK2 | |
| SCHEMBL20552165 | 0.81 | NAMPT (0.48) | GRM1GRM5NAMPTJAK2JAK3 | |
| SCHEMBL31379931 | 0.80 | GRM1 (0.58) | GRM1GRM5NAMPTPDK4PDE10A | |
| SCHEMBL20552141 | 0.77 | TP53 (0.50) | GRM1GRM5NAMPTPDK4PDE10A | |
| SCHEMBL20551736 | 0.75 | JAK2 (0.52) | NAMPTJAK2JAK3PTK2 | |
| SCHEMBL31310816 | 0.74 | ACP1 (0.40) | JAK2JAK3PTK2 | |
| SCHEMBL20552488 | 0.74 | ACP1 (0.40) | JAK2JAK3PTK2 | |
| SCHEMBL2239831 | 0.74 | NAMPT (0.66) | GRM1GRM5NAMPTPDK4TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025027560-A1 | NEW RHOJ/CDC42 INHIBITORS DEVELOPED FOR THE TREATMENT OF CANCER, BENIGN TUMORS, RETINAL DISORDERS, VASCULAR DISORDERS, AND CARDIOMYOPATHIES | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-02-06 | — | — | WO | disclosed |