Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670544 | 1.00 | PTGS1 (0.58) | PTGS1AKR1C3AKR1C2MAOBCYP1A2 | |
| SCHEMBL6231623 | 0.96 | CYP1A2 (0.55) | PTGS1AKR1C3AKR1C2MAOBCYP1A2 | |
| SCHEMBL3716715 | 0.84 | TAAR1 (0.68) | PTGS1AKR1C3AKR1C2MAOBCYP1A2 | |
| Hydrochloric Acid SCHEMBL11267009 | 0.82 | TAAR1 (0.66) | PTGS1AKR1C3AKR1C2MAOBCYP1A2 | |
| SCHEMBL9016348 | 0.82 | ASIC3 (0.57) | CYP1A2CYP2A6LOXL2TAAR1 | |
| SCHEMBL6348328 | 0.82 | KDM4E (0.48) | MAOBCYP1A2KDM4ELMNACYP3A4 | |
| SCHEMBL9123911 | 0.81 | TAAR1 (0.63) | PTGS1AKR1C3AKR1C2MAOBCYP1A2 | |
| SCHEMBL2056268 | 0.81 | AKR1C3 (0.59) | PTGS1AKR1C3AKR1C2CYP1A2KDM4E | |
| SCHEMBL15345375 | 0.80 | NQO1 (0.48) | AKR1C3AKR1C2CYP1A2NPC1LMNA | |
| SCHEMBL4951818 | 0.80 | MAOB (0.73) | MAOBCYP1A2TP53CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076284-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | DELPHIA THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| CN-119707886-A | Preparation method of amine compound | 江苏丽源医药有限公司 | 2025-03-28 | — | — | CN | disclosed |