SCHEMBL31380439

SCHEMBL31380439

CCOC(=O)c1ccc(Cl)c(O)c1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.53
CYP4A11 Q02928 1/20 0.53
TSHR P16473 1/20 0.52
CA12 O43570 4/20 0.51
CA1 P00915 4/20 0.51
CA2 P00918 4/20 0.51
CA7 P43166 4/20 0.51
CA9 Q16790 4/20 0.51
CA14 Q9ULX7 4/20 0.51
BAZ2B Q9UIF8 1/20 0.49
BAZ2A Q9UIF9 1/20 0.49
METTL3 Q86U44 1/20 0.48
ALDH1A1 P00352 2/20 0.45
HSD17B10 Q99714 1/20 0.45
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3436904 1.00 CYP4F2 (0.53) CYP4F2CYP4A11TSHRCA12CA1
SCHEMBL6311143 0.86 CYP4F2 (0.53) CYP4F2CYP4A11TSHRCA12CA1
SCHEMBL27259744 0.86 CYP4F2 (0.55) CYP4F2CYP4A11TSHRCA12CA1
SCHEMBL7582549 0.81 CYP4F2 (0.54) CYP4F2CYP4A11TSHRCA12CA1
SCHEMBL7418272 0.80 ABL1 (0.47) TSHRCA12CA1CA2CA7
SCHEMBL30960327 0.79 TSHR (0.65) TSHRCA12CA1CA2CA7
SCHEMBL4262832 0.79 TSHR (0.65) TSHRCA12CA1CA2CA7
SCHEMBL7582552 0.79 CYP4F2 (0.49) CYP4F2CYP4A11TSHRCA12CA1
SCHEMBL27993113 0.79 TSHR (0.55) CYP4F2CYP4A11TSHRCA12CA1
SCHEMBL30093973 0.79 CYP4F2 (0.55) CYP4F2CYP4A11TSHRCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707655-A 3-Hydroxy-2, 4-dichloro acetophenone prepared by one-pot method and preparation method thereof 江西永通科技股份有限公司 2025-03-28 CN claimed
CN-119707655-A 3-Hydroxy-2, 4-dichloro acetophenone prepared by one-pot method and preparation method thereof 江西永通科技股份有限公司 2025-03-28 CN disclosed