Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27980809 | 0.87 | METTL3 (0.43) | TSHRMETTL3CA12CA1CA2 | |
| SCHEMBL27259744 | 0.85 | CYP4F2 (0.55) | TSHRMETTL3CA12CA1CA2 | |
| SCHEMBL3699729 | 0.84 | TSHR (0.63) | TSHRMETTL3CA12CA1CA2 | |
| SCHEMBL7966180 | 0.81 | PTGS2 (0.53) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL1760338 | 0.80 | TSHR (0.53) | TSHRMETTL3CA12CA1CA2 | |
| SCHEMBL3436904 | 0.79 | CYP4F2 (0.53) | TSHRMETTL3CA12CA1CA2 | |
| SCHEMBL31380439 | 0.79 | CYP4F2 (0.53) | TSHRMETTL3CA12CA1CA2 | |
| SCHEMBL6689492 | 0.78 | TSHR (0.47) | TSHRMETTL3CA12CA1CA2 | |
| SCHEMBL28644344 | 0.77 | TSHR (0.54) | TSHRALDH1A1HSD17B10MAPK1MEN1 | |
| SCHEMBL28731066 | 0.77 | ALDH1A1 (0.50) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379568-A | Quinazolinedione derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-02-25 | — | — | CN | disclosed |