Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143987 | 0.86 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL3148083 | 0.84 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL3146536 | 0.84 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL3156446 | 0.83 | CRHR1 (0.80) | CRHR1 | |
| SCHEMBL3151576 | 0.83 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL3152661 | 0.81 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL3138265 | 0.80 | CRHR1 (0.89) | CRHR1 | |
| SCHEMBL3138425 | 0.80 | CRHR1 (0.79) | CRHR1 | |
| SCHEMBL3146978 | 0.80 | CRHR1 (0.79) | CRHR1 | |
| SCHEMBL3142550 | 0.78 | CRHR1 (0.85) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2154139-A1 | BICYCLIC HETEROCYCLIC COMPOUND | ONO Pharmaceutical Co., Ltd. (JP) | 2010-02-17 | — | — | EP | disclosed |