Cyclohexene

Cyclohexene

SCHEMBL3138151

C1=CCCCC1.CC(=O)O

nearest known ligand 0.47

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cyclohexene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.47
LCK P06239 1/20 0.47
FYN P06241 1/20 0.47
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexene SCHEMBL23409884 1.00 FFAR3 (0.47) FFAR3LCKFYNLMNA
Acetic Acid SCHEMBL29062607 0.97 FFAR3 (0.44) FFAR3LCKFYN
Acetic Acid SCHEMBL27952408 0.97 FFAR3 (0.44) FFAR3LCKFYN
Acetic Acid SCHEMBL4983972 0.97 FFAR3 (0.44) FFAR3LCKFYN
Cyclohexene SCHEMBL7152357 0.97 FFAR3 (0.44) FFAR3LCKFYN
Acetic Acid SCHEMBL4983986 0.97 FFAR3 (0.44) FFAR3LCKFYN
Cyclopentene SCHEMBL1523429 0.93
Cyclohexene SCHEMBL1999560 0.90 LMNA (0.43) FFAR3LCKFYNLMNA
Cyclohexene SCHEMBL27709579 0.87 FFAR3 (0.35) FFAR3LCKFYN
Acetic Acid SCHEMBL29159728 0.86 FFAR3 (0.54) FFAR3LCKFYNLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105949370-A High-strength rapid water absorption resin and preparation method thereof 青岛科技大学 2016-09-21 CN claimed
CN-104284884-A Fluoro-substituted (3R,4R,5S) -5-guanidino-4-acetamido-3- (pentan-3-yloxy) cyclohexene-1-carboxylic acids, esters thereof and uses thereof IVACHTCHENKO ALEXANDRE VASILEVICH 2015-01-14 CN claimed
CN-114904563-A ZSM-5 supported noble metal catalyst, preparation method and application 江苏扬农化工集团有限公司 2022-08-16 CN disclosed
CN-108291050-B Polymeric flame retardant mixtures 科莱恩塑料和涂料有限公司 2021-06-25 CN disclosed
CN-107434767-B Method for preparing cyclohexanol and cyclohexyl acetate from cyclohexene and acetic acid 中国石油化工股份有限公司 2020-07-24 CN disclosed
US-20180346739-A1 POLYMERIC FLAME RETARDANT MIXTURES CLARIANT PLASTICS & COATINGS LTD (CH) 2018-12-06 US disclosed
CN-108821978-A A kind of method that selective reduction prepares 1- cyclohexene ethamine 辽宁东科药业有限公司 2018-11-16 CN disclosed
CN-107434767-A A kind of method that cyclohexanol and cyclohexyl acetate are prepared using cyclohexene and acetic acid 中国石油化工股份有限公司 2017-12-05 CN disclosed
CN-105949370-A High-strength rapid water absorption resin and preparation method thereof 青岛科技大学 2016-09-21 CN disclosed
CN-105859566-A 2-(1-cyclohexenyl)ethylamine and preparation method thereof 叶芳 2016-08-17 CN disclosed
CN-105669465-A Preparing method of 1-cyclohexene ethylamine 苏州艾缇克药物化学有限公司 2016-06-15 CN disclosed
CN-104284884-A Fluoro-substituted (3R,4R,5S) -5-guanidino-4-acetamido-3- (pentan-3-yloxy) cyclohexene-1-carboxylic acids, esters thereof and uses thereof IVACHTCHENKO ALEXANDRE VASILEVICH 2015-01-14 CN disclosed
US-20100076217-A1 ACYLOXYLATION CATALYST AND PROCESS FOR ITS PRODUCTION SHOWA DENKO K.K. (JP) 2010-03-25 US disclosed
EP-2099563-A1 ACYLOXYLATION CATALYST AND PROCESS FOR ITS PRODUCTION Showa Denko K.K. (JP) 2009-09-16 EP disclosed
WO-2008075588-A1 ACYLOXYLATION CATALYST AND PROCESS FOR ITS PRODUCTION SHOWA DENKO K.K. (JP) 2008-06-26 WO disclosed