Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 10/20 | 0.50 |
| ▸ | TNKS | O95271 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | PARP12 | Q9H0J9 | 2/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31381958 | 0.99 | TIPARP (0.49) | TIPARPTNKSPARP10PARP12TNKS2 | |
| SCHEMBL25225065 | 0.89 | POLB (0.49) | TIPARPTNKSPARP10PARP12TNKS2 | |
| Hydrochloric Acid SCHEMBL31381862 | 0.88 | POLB (0.48) | TIPARPTNKSPARP10PARP12TNKS2 | |
| Hydrochloric Acid SCHEMBL31381926 | 0.87 | LMNA (0.47) | TIPARPTNKSPARP10PARP12TNKS2 | |
| SCHEMBL31381930 | 0.85 | TIPARP (0.51) | TIPARPTNKSPARP10PARP12TNKS2 | |
| SCHEMBL30479877 | 0.83 | TIPARP (0.51) | TIPARPTNKSPARP10PARP12TNKS2 | |
| Hydrochloric Acid SCHEMBL31381891 | 0.83 | KDM4E (0.61) | LMNASMN1; SMN2POLBKDM4EABL1 | |
| SCHEMBL31381895 | 0.82 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2POLBKDM4ESLC6A9 | |
| SCHEMBL31381925 | 0.82 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL31381899 | 0.82 | TIPARP (0.50) | TIPARPTNKSPARP10PARP12TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025045246-A1 | PARP7 INHIBITOR AND USE THEREOF | 重庆华森英诺生物科技有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-119330972-A | PARP7 inhibitor and application thereof | 重庆华森英诺生物科技有限公司 | 2025-01-21 | — | — | CN | disclosed |