Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.38 |
| ▸ | MDK | P21741 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CD69 | Q07108 | 1/20 | 0.34 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30980707 | 0.88 | MAPK1 (0.43) | MAPK1ALDH1A1THRBLGALS8LGALS3 | |
| SCHEMBL30980636 | 0.86 | MAPK1 (0.36) | MAPK1ALDH1A1THRBLGALS8LGALS3 | |
| SCHEMBL30980704 | 0.85 | MAPK1 (0.52) | MAPK1ALDH1A1THRBLGALS8LGALS3 | |
| SCHEMBL30980773 | 0.84 | MAPK1 (0.40) | MAPK1ALDH1A1THRBLGALS8LGALS3 | |
| SCHEMBL30980606 | 0.83 | MAPK1 (0.47) | MAPK1ALDH1A1THRBLGALS8LGALS3 | |
| SCHEMBL30980757 | 0.83 | MAPK1 (0.46) | MAPK1ALDH1A1THRBLGALS8LGALS3 | |
| SCHEMBL30980683 | 0.82 | OGA (0.44) | MAPK1ALDH1A1THRB | |
| SCHEMBL30980511 | 0.81 | MAPK1 (0.53) | MAPK1ALDH1A1THRBLGALS8LGALS3 | |
| SCHEMBL31384251 | 0.81 | MAPK1 (0.53) | MAPK1ALDH1A1THRBLGALS8LGALS3 | |
| SCHEMBL31384238 | 0.81 | MAPK1 (0.53) | MAPK1ALDH1A1THRBLGALS8LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025035040-A1 | LYSOSOMAL TARGETING BIFUNCTIONAL MOLECULES FOR DEGRADATION OF MUSCLE-SPECIFIC KINASE AUTOANTIBODIES | LYCIA THERAPEUTICS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |