SCHEMBL31384337

SCHEMBL31384337

Cc1ccc(-c2nnc(C(=O)NN)o2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.53
SMPD1 P17405 2/20 0.53
KDM4E B2RXH2 6/20 0.51
ADCY1 Q08828 1/20 0.49
RAB9A P51151 5/20 0.49
ALDH1A1 P00352 5/20 0.49
NPC1 O15118 4/20 0.49
HSD17B10 Q99714 4/20 0.49
TP53 P04637 1/20 0.49
KMT2A Q03164 3/20 0.49
HPGD P15428 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
POLB P06746 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
ESR1 P03372 1/20 0.48
PKM P14618 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30968155 0.85 SMPD1 (0.61) HDAC8SMPD1KDM4EADCY1RAB9A
SCHEMBL31384264 0.84 SMPD1 (0.73) SMPD1KDM4EADCY1RAB9AALDH1A1
SCHEMBL15498835 0.84 PTPN1 (0.63) HDAC8SMPD1KDM4ERAB9AALDH1A1
SCHEMBL31384372 0.84 NPC1 (0.56) KDM4ERAB9AALDH1A1NPC1HSD17B10
SCHEMBL30968143 0.83 PKM (0.61) SMPD1KDM4ERAB9AALDH1A1NPC1
SCHEMBL27914847 0.82 NPC1 (0.56) HDAC8SMPD1KDM4EADCY1RAB9A
SCHEMBL31384301 0.81 KDM4E (0.61) HDAC8SMPD1KDM4EADCY1RAB9A
Hydrochloric Acid SCHEMBL27933406 0.80 NPC1 (0.55) HDAC8SMPD1KDM4EADCY1RAB9A
SCHEMBL19075480 0.80 PTPN1 (0.72) HDAC8SMPD1KDM4EADCY1RAB9A
SCHEMBL31384299 0.80 HDAC8 (0.57) HDAC8SMPD1RAB9AALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504731-A Naringenin derivative containing 1,3, 4-oxadiazole acylhydrazone structure and preparation method thereof 广东省科学院测试分析研究所(中国广州分析测试中心) 2025-02-25 CN disclosed