Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.38 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26555615 | 0.89 | GSR (0.55) | GSRDPP8DPP9DPP7GNAI3 | |
| SCHEMBL29775136 | 0.89 | GSR (0.55) | GSRDPP8DPP9DPP7GNAI3 | |
| SCHEMBL18263221 | 0.89 | GSR (0.55) | GSRDPP8DPP9DPP7GNAI3 | |
| SCHEMBL30254803 | 0.89 | GSR (0.55) | GSRDPP8DPP9DPP7GNAI3 | |
| SCHEMBL22199726 | 0.88 | FOLH1 (0.45) | GSRDPP8DPP9DPP7GNAI3 | |
| SCHEMBL7570529 | 0.87 | DPP8 (0.51) | GSRDPP8DPP9DPP7GNAI3 | |
| Glycine SCHEMBL29096238 | 0.86 | GSR (0.51) | GSRDPP8DPP9DPP7GNAI3 | |
| SCHEMBL30798022 | 0.86 | GSR (0.51) | GSRDPP8DPP9DPP7GNAI3 | |
| SCHEMBL30797910 | 0.86 | GSR (0.51) | GSRDPP8DPP9DPP7GNAI3 | |
| SCHEMBL27584028 | 0.85 | DPP8 (0.50) | GSRDPP8DPP9DPP7GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250195606-A1 | METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS | CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2025-06-19 | — | — | US | disclosed |
| US-12263202-B2 | Method of treating melanocortin-4 receptor pathway-associated disorders | RHYTHM PHARMACEUTICALS, INC. (US) | 2025-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12263202-B2 | Method of treating melanocortin-4 receptor pathway-associated disorders | MC4R, MC5R, MC3R | GSR 2051/4885DPP8 1811/4885DPP9 2171/4885 |
| US-20250195606-A1 | METHOD OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS | MC4R, MC5R, MC3R | GSR 2051/4885DPP8 1811/4885DPP9 2171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.