SCHEMBL7570529

SCHEMBL7570529

NCCCC[C@H](NC(=O)[C@@H](N)CCCCN)C(N)=O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 2/20 0.51
DPP9 Q86TI2 2/20 0.51
DPP7 Q9UHL4 2/20 0.51
GSR P00390 1/20 0.50
GNAI3 P08754 1/20 0.47
GNAO1 P09471 1/20 0.47
GNAI1 P63096 1/20 0.47
NOD1 Q9Y239 1/20 0.46
DPP4 P27487 1/20 0.45
HPGDS O60760 1/20 0.43
FOLH1 Q04609 1/20 0.42
ERAP2 Q6P179 1/20 0.41
ERAP1 Q9NZ08 1/20 0.41
LNPEP Q9UIQ6 1/20 0.41
MMP2 P08253 1/20 0.41
SIRT6 Q8N6T7 1/20 0.40
SIRT1 Q96EB6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29740503 0.97 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL31325363 0.97 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL29805332 0.97 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL29462129 0.97 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL29893154 0.97 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL30118075 0.91 GSR (0.44) DPP8DPP9DPP7GSRGNAI3
SCHEMBL16152404 0.91 GNAI3 (0.62) DPP8DPP9DPP7GSRGNAI3
SCHEMBL30799418 0.90 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL31614336 0.90 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL16117343 0.90 TLR2 (0.43) DPP8DPP9DPP7GSRGNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4482853-A1 ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES RESOTHER PHARMA A/S (DK) 2025-01-01 EP claimed
CN-118891273-A Annexin A1 derived polypeptide analogs 雷索特制药股份有限公司 2024-11-01 CN claimed
EP-3497114-B1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES OLIPASS CORP (KR) 2024-10-16 EP claimed
CN-115944738-B Application of complement C3 cracking inhibitor in preparation of medicine for treating diabetic cardiomyopathy 华中科技大学同济医学院附属同济医院 2024-06-18 CN claimed
US-20230303640-A1 EXENDIN-4 PEPTIDE ANALOGS TXP PHARMA AG (CH) 2023-09-28 US claimed
US-20230295255-A1 ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES RESOTHER PHARMA APS (DK) 2023-09-21 US claimed
WO-2023161323-A1 ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES RESOTHER PHARMA A/S (DK) 2023-08-31 WO claimed
EP-4200320-A1 ANNEXIN A1-DERIVED POLYPEPTIDE ANALOGUES RESOTHER PHARMA A/S (DK) 2023-06-28 EP claimed
US-20260000626-A1 POLYMERIC NANOPARTICLES FOR LONG ACTING DELIVERY OF A PEPTIDE AND METHODS OF MAKING AND USING THEREOF UNIV BROWN (US) 2026-01-01 US disclosed
US-20250319163-A1 TREATMENT OF TYPE 2 DIABETES MELLITUS SANOFI SA (FR) 2025-10-16 US disclosed
US-20250236656-A1 MULTIMERIC POLYPEPTIDES AND USES THEREOF Amide Technologies (US) 2025-07-24 US disclosed
EP-4582441-A2 MULTIMERIC POLYPEPTIDES AND USES THEREOF Amide Technologies (US) 2025-07-09 EP disclosed
US-20250171515-A1 AAV VECTORS FOR DELIVERY OF GLP-1 RECEPTOR AGONIST FUSIONS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-05-29 US disclosed
EP-4489770-A1 AAV VECTORS FOR DELIVERY OF GLP-1 RECEPTOR AGONIST FUSIONS The Trustees of the University of Pennsylvania (US) 2025-01-15 EP disclosed
WO-2022046809-A1 VIRAL VECTOR ENCODING GLP-1 RECEPTOR AGONIST FUSIONS AND USES THEREOF IN TREATING METABOLIC DISEASES IN FELINES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2022-03-03 WO disclosed
WO-2022046815-A1 VIRAL VECTORS ENCODING GLP-1 RECEPTOR AGONIST FUSIONS AND USES THEREOF IN TREATING METABOLIC DISEASES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2022-03-03 WO disclosed
US-20080260829-A1 Bone morphogenic proteins (bmp); cell adhesion modulating agent; peptidomimetics of cyclic peptides comprising classical cadherin cell adhesion recognition (CAR) sequences; modulate cell adhesion and improve drug delivery NEW YORK SOCIETY FOR THE RUPTURED AND CRIPPLED MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY (US) 2008-10-23 US disclosed
CN-1406124-A Nasal administration of cyclic peptide compositions BASILEA PHARMACUEITCA AG (CH) 2003-03-26 CN disclosed
EP-1237581-A1 USE OF CATIONIC LIPIDS FOR INTRACELLULAR PROTEIN DELIVERY Gene Therapy Systems, Inc. (US) 2002-09-11 EP disclosed
WO-2001043778-A1 USE OF CATIONIC LIPIDS FOR INTRACELLULAR PROTEIN DELIVERY GENE THERAPY SYSTEMS, INC. (US) 2001-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260000626-A1 POLYMERIC NANOPARTICLES FOR LONG ACTING DELIVERY OF A PEPTIDE AND METHODS OF MAKING AND USING THEREOF VEGFA, IAPP, NPPA DPP8 2781/4885DPP9 1118/4885DPP7 2068/4885
US-20080260829-A1 Bone morphogenic proteins (bmp); cell adhesion modulating agent; peptidomimetics of cyclic peptides comprising classical cadherin cell adhesion recognition (CAR) sequences; modulate cell adhesion and improve drug delivery BMP1, BMP2, BMP4 DPP8 2732/4885DPP9 2265/4885DPP7 2657/4885
US-20250236656-A1 MULTIMERIC POLYPEPTIDES AND USES THEREOF GIPR, GRPR, SCTR DPP8 170/4885DPP9 327/4885DPP7 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.