SCHEMBL31385237

SCHEMBL31385237

NC(=O)c1ncnc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 1/20 0.52
PI4K2B Q8TCG2 1/20 0.52
PI4K2A Q9BTU6 1/20 0.52
PI4KB Q9UBF8 1/20 0.52
LCK P06239 1/20 0.51
MAP2K3 P46734 1/20 0.51
MAP2K6 P52564 1/20 0.51
BTK Q06187 1/20 0.51
MAP3K19 Q56UN5 1/20 0.51
NEK10 Q6ZWH5 1/20 0.51
PDE4A P27815 1/20 0.47
PDE4B Q07343 1/20 0.47
PDE4C Q08493 1/20 0.47
PDE4D Q08499 1/20 0.47
LMNA P02545 1/20 0.46
ADORA3 P0DMS8 1/20 0.45
ADORA2A P29274 1/20 0.44
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
KMT2A Q03164 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17099640 1.00 PI4KA (0.52) PI4KAPI4K2BPI4K2API4KBLCK
SCHEMBL27554878 0.82 PI4KA (0.53) PI4KAPI4K2BPI4K2API4KBPDE4A
SCHEMBL2833079 0.82 SMN1; SMN2 (0.52) PI4KAPI4K2BPI4K2API4KBPDE4A
SCHEMBL30902246 0.82 SMN1; SMN2 (0.52) PI4KAPI4K2BPI4K2API4KBPDE4A
Lithium Ion SCHEMBL21818896 0.81 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBPDE4A
SCHEMBL11558582 0.81 PI4KA (0.57) PI4KAPI4K2BPI4K2API4KBPDE4A
Hydrochloric Acid SCHEMBL20269711 0.79 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBPDE4A
SCHEMBL27874136 0.78 PI4KA (0.44) PI4KAPI4K2BPI4K2API4KBPDE4A
4-Aminoquinazoline SCHEMBL27977310 0.77 PI4KA (0.81) PI4KAPI4K2BPI4K2API4KBLCK
SCHEMBL15500822 0.77 RXFP1 (0.51) LMNAADORA3NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025224270-A1 NEW HETEROCYCLIC COMPOUNDS REDUCING THE TASL PROTEIN LEVEL SOLGATE GMBH (AT) 2025-10-30 WO disclosed
CN-119119035-A RIPK1 kinase target inhibitor and preparation method and application thereof 中山大学 2024-12-13 CN disclosed