Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2833079 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTALDH1A1ADORA2AADORA3 | |
| SCHEMBL31385237 | 0.82 | PI4KA (0.52) | SMN1; SMN2MAPTALDH1A1ADORA2AADORA3 | |
| SCHEMBL17099640 | 0.82 | PI4KA (0.52) | SMN1; SMN2MAPTALDH1A1ADORA2AADORA3 | |
| Lithium Ion SCHEMBL21818896 | 0.82 | PI4KA (0.47) | SMN1; SMN2MAPTALDH1A1ADORA2AADORA3 | |
| SCHEMBL28607066 | 0.80 | ADORA2A (0.50) | SMN1; SMN2MAPTALDH1A1ADORA2AADORA3 | |
| SCHEMBL27874136 | 0.79 | PI4KA (0.44) | SMN1; SMN2MAPTALDH1A1ADORA2AADORA3 | |
| SCHEMBL15500822 | 0.78 | RXFP1 (0.51) | SMN1; SMN2MAPTALDH1A1ADORA3LMNA | |
| SCHEMBL16664897 | 0.78 | RAB9A (0.50) | MAPTALDH1A1ADORA3PI4KAPI4K2B | |
| SCHEMBL15500953 | 0.78 | LMNA (0.47) | SMN1; SMN2MAPTALDH1A1ADORA2AADORA3 | |
| SCHEMBL21834591 | 0.77 | KMT2A (0.56) | MAPTALDH1A1ADORA2AADORA3PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957219-A | Pyridine derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |