Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753366 | 0.88 | KLK5 (0.47) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL3753362 | 0.88 | KLK5 (0.47) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL25361007 | 0.88 | KLK5 (0.47) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL7851771 | 0.86 | PPARA (0.43) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL28684646 | 0.85 | CYP1A2 (0.46) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL28684647 | 0.85 | CYP1A2 (0.46) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL17291652 | 0.85 | PPARA (0.57) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL20974785 | 0.85 | PPARA (0.57) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL15448116 | 0.85 | PPARA (0.57) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL31385404 | 0.83 | PPARA (0.46) | PPARAPPARGCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038747-A1 | MODIFIED THIOSTREPTON-INSPIRED COMPOUNDS FOR TREATMENT OF CANCER AND PREPARATION THEREOF | RS ONCOLOGY, LLC (US) | 2025-02-20 | — | — | WO | disclosed |