Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | MST1R | Q04912 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 3/20 | 0.32 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.31 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385354 | 1.00 | CDK5 (0.47) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL21152310 | 0.69 | CDK5 (0.44) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL1333810 | 0.64 | CLK4 (1.00) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL24466480 | 0.63 | CDK5 (0.55) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL17141660 | 0.63 | CLK4 (0.46) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL21153005 | 0.62 | KDR (0.43) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL24147834 | 0.62 | CLK4 (0.53) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL25260852 | 0.62 | PIM1 (0.53) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL25411512 | 0.62 | CLK4 (0.53) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL1334392 | 0.62 | CLK4 (0.53) | CDK5DYRK1ACLK4PIM1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038747-A1 | MODIFIED THIOSTREPTON-INSPIRED COMPOUNDS FOR TREATMENT OF CANCER AND PREPARATION THEREOF | RS ONCOLOGY, LLC (US) | 2025-02-20 | — | — | WO | disclosed |