SCHEMBL31386

SCHEMBL31386

C=CCNC(=O)CC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7995237 0.85
SCHEMBL26091851 0.83 SMN1; SMN2 (0.68)
SCHEMBL11565199 0.83
SCHEMBL8519439 0.83
SCHEMBL6147435 0.81 SMN1; SMN2 (0.48)
SCHEMBL10337028 0.81 NQO2 (0.42)
SCHEMBL1958588 0.81 SMN1; SMN2 (0.81)
SCHEMBL28276624 0.80 SMN1; SMN2 (0.52)
SCHEMBL5494155 0.79
SCHEMBL206601 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 473 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250092201-A1 ULTRA TOUGH GLASSY THERMOSET SYNTHESIZED USING A CURABLE LIQUID RESIN UNIVERSITY OF UTAH RESEARCH FOUNDATION 2025-03-20 US claimed
WO-2024015425-A1 HERBICIDAL BENZOXAZINES FMC CORPORATION (US) 2024-01-18 WO claimed
WO-2023229380-A1 HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF 주식회사 엘지화학 2023-11-30 WO claimed
EP-4263518-A1 NEW QUINAZOLINONE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2023-10-25 EP claimed
EP-4263541-A1 NEW ARYL-PYRIDO-PYRIMIDIN-ONE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2023-10-25 EP claimed
US-20230331682-A1 NEW QUINAZOLINONE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2023-10-19 US claimed
US-20230322776-A1 NEW ARYL-PYRIDO-PYRIMIDIN-ONE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2023-10-12 US claimed
US-20230159564-A1 2-Oxo-Thiazole Derivatives as A2A Inhibitors and Compounds for Use in the Treatment of Cancers iTeos Belgium SA (BE) 2023-05-25 US claimed
WO-2022129260-A1 NEW ARYL-PYRIDO-PYRIMIDIN-ONE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2022-06-23 WO claimed
WO-2022129259-A1 NEW QUINAZOLINONE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2022-06-23 WO claimed
US-5312960-A Fungicidal 2-methoximinocarboxylic esters BAYER AKTIENGESELLSCHAFT (DE) 1994-05-17 US claimed
EP-0546387-A1 Substituted oximetheramides BAYER AG (DE) 1993-06-16 EP claimed
EP-0542795-A1 TNF INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1993-05-26 EP claimed
EP-0529974-A1 Fungicidal 2-aryl-2-cyano-2-(aryloxyalkyl)ethyl-1,2,4-triazoles ROHM AND HAAS COMPANY (US) 1993-03-03 EP claimed
WO-1992002220-A1 TNF INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1992-02-20 WO claimed
EP-0464381-A2 2-Methoxyiminocarboxylic acid esters BAYER AG (DE) 1992-01-08 EP claimed
EP-0410238-A2 Pyridazinone derivatives BAYER AG (DE) 1991-01-30 EP claimed
US-4755505-A 1-[2-(dialkylamino)alkyl]-4,5-dihydro-4-(aryl)-1-benzazocine-2,6(1H,3H)-diones as anti-arrhythmic agents AMERICAN HOME PRODUCTS CORPORATION (US) 1988-07-05 US claimed
EP-0241826-A1 3-Amino-2-cyano-acrylic acid esters BAYER AG (DE) 1987-10-21 EP claimed
EP-0023028-B1 MIXTURES OF OPTICAL BRIGHTENERS AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1982-12-15 EP claimed