Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138597 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRMAPTKMT2AFAAH | |
| SCHEMBL31386 | 0.81 | — | — | |
| SCHEMBL17859667 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRMAPTKMT2AFAAH | |
| SCHEMBL17859666 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRMAPTKMT2AFAAH | |
| SCHEMBL252121 | 0.78 | TSHR (0.56) | SMN1; SMN2TSHRMAPTKMT2AFAAH | |
| SCHEMBL252883 | 0.78 | TSHR (0.39) | SMN1; SMN2TSHRMAPTKMT2AFAAH | |
| SCHEMBL8060600 | 0.78 | TSHR (0.56) | SMN1; SMN2TSHRMAPTKMT2AFAAH | |
| SCHEMBL175574 | 0.78 | TSHR (0.39) | SMN1; SMN2TSHRMAPTKMT2AFAAH | |
| SCHEMBL1248748 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRMAPTKMT2AFAAH | |
| SCHEMBL19729322 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2TSHRMAPTKMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603858-A2 | KCNQ CHANNEL MODULATING COMPOUNDS AND THEIR PHARMACEUTICAL USE | NeuroSearch A/S (DK) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080377-A2 | KCNQ CHANNEL MODULATING COMPOUNDS AND THEIR PHARMACEUTICAL USE | NEUROSEARCH A/S (DK) | 2004-09-23 | — | — | WO | disclosed |