Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040438 | 0.94 | NAMPT (0.54) | NPSR1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL15952633 | 0.91 | ATM (0.47) | PDE4BNPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9409412 | 0.86 | PDE4B (0.59) | PDE4BKMT2AALDH1A1MAPTGPR119 | |
| SCHEMBL31015904 | 0.86 | NPSR1 (0.47) | PDE4BNPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL26092608 | 0.86 | NPSR1 (0.47) | PDE4BNPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL31015900 | 0.86 | NPSR1 (0.47) | PDE4BNPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL26428976 | 0.86 | NPSR1 (0.47) | PDE4BNPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30349607 | 0.86 | NPSR1 (0.47) | PDE4BNPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL26428969 | 0.86 | NPSR1 (0.47) | PDE4BNPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3040729 | 0.85 | FDFT1 (0.53) | PDE4BKMT2AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727591-A1 | SMARCA2 DEGRADERS AND USES THEREOF | Astrazeneca AB (SE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256988-A1 | SMARCA2 DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2024-12-19 | — | — | WO | disclosed |