Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 10/20 | 0.56 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.52 |
| ▸ | MET | P08581 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | NRAS | P01111 | 1/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 4/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.48 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | CCNH | P51946 | 1/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31387007 | 0.86 | FLT3 (0.53) | FLT3METKDRFGFR3NEK2 | |
| SCHEMBL25764532 | 0.84 | FLT3 (0.53) | FLT3IRAK4METPDE3BPDE3A | |
| SCHEMBL24231604 | 0.81 | FLT3 (0.58) | FLT3IRAK4NRASIRAK1KDR | |
| SCHEMBL24231869 | 0.81 | FLT3 (0.58) | FLT3IRAK4NRASIRAK1KDR | |
| SCHEMBL24231553 | 0.81 | FLT3 (0.44) | FLT3IRAK4NRASIRAK1KDR | |
| SCHEMBL24232046 | 0.80 | FLT3 (0.47) | FLT3IRAK4NRASCCNT1USP30 | |
| SCHEMBL24231463 | 0.80 | IRAK4 (0.48) | FLT3IRAK4CCNT1USP30 | |
| SCHEMBL24231985 | 0.80 | FLT3 (0.46) | FLT3IRAK4NRASCCNT1USP30 | |
| SCHEMBL24231649 | 0.80 | FLT3 (0.48) | FLT3IRAK4NRASCCNT1USP30 | |
| SCHEMBL24574418 | 0.79 | IRAK4 (0.49) | FLT3IRAK4METNRASIRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038525-A1 | FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS FOR TREATING CELL PROLIFERATIVE DISEASES OR CONDITIONS | BIOVENTURES, LLC (US) | 2025-02-20 | — | — | WO | claimed |
| WO-2025038525-A1 | FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS FOR TREATING CELL PROLIFERATIVE DISEASES OR CONDITIONS | BIOVENTURES, LLC (US) | 2025-02-20 | — | — | WO | disclosed |