Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 11/20 | 0.53 |
| ▸ | FLT3 | P36888 | 3/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.46 |
| ▸ | MERTK | Q12866 | 3/20 | 0.46 |
| ▸ | GAS6 | Q14393 | 3/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2008327 | 0.99 | MLNR (0.52) | MLNRFLT3TYRO3MERTKGAS6 | |
| SCHEMBL2010299 | 0.89 | MLNR (0.68) | MLNRFLT3TYRO3MERTKGAS6 | |
| SCHEMBL2013240 | 0.87 | MLNR (0.69) | MLNRCYP3A4CYP2D6GHSR | |
| Hydrochloric Acid SCHEMBL2003648 | 0.86 | MLNR (0.68) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL2011342 | 0.82 | MLNR (0.45) | MLNRFLT3TYRO3MERTKGAS6 | |
| SCHEMBL3134470 | 0.81 | MLNR (0.50) | MLNRFLT3TYRO3MERTKGAS6 | |
| SCHEMBL2006917 | 0.78 | MLNR (0.69) | MLNRFLT3TYRO3MERTKGAS6 | |
| SCHEMBL2010214 | 0.77 | MLNR (0.46) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL2011532 | 0.70 | MLNR (0.50) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL2011340 | 0.70 | MLNR (0.53) | MLNRCYP3A4CYP2D6GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960390-B1 | BIARYL COMPOUNDS USEFUL AS AGONISTS OF THE GPR38 RECEPTOR | GLAXO GROUP LTD (GB) | 2010-07-21 | — | — | EP | claimed |