Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31387097 | 0.91 | SMN1; SMN2 (0.62) | SMN1; SMN2HTR1AHTR2ADRD3ADRA2A | |
| SCHEMBL15477410 | 0.89 | SMN1; SMN2 (0.66) | SMN1; SMN2HTR1AHTR2ADRD3ADRA2A | |
| SCHEMBL31387144 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2HTR1AHTR2ADRD3ADRA2A | |
| SCHEMBL17554051 | 0.87 | TP53 (0.54) | SMN1; SMN2HTR1AHTR2ADRD3ADRA2A | |
| SCHEMBL11341680 | 0.83 | HDAC2 (0.76) | SMN1; SMN2HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL9661355 | 0.82 | DRD3 (0.61) | SMN1; SMN2HTR1AHTR2ADRD3ADRA2A | |
| SCHEMBL30560454 | 0.82 | KDM4E (0.62) | SMN1; SMN2HTR1AALDH1A1TSHR | |
| SCHEMBL17554121 | 0.82 | KDM4E (0.62) | SMN1; SMN2HTR1AALDH1A1TSHR | |
| SCHEMBL17554157 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL17873924 | 0.81 | SMN1; SMN2 (0.76) | SMN1; SMN2HTR1AHTR2ADRD3NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119255993-A | Thiazole derivative compound and use thereof | 奥托泰利克生物公司 | 2025-01-03 | — | — | CN | claimed |
| CN-119585248-A | Heteroaryl derivatives as DDR inhibitors | 奇斯药制品公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119255993-A | Thiazole derivative compound and use thereof | 奥托泰利克生物公司 | 2025-01-03 | — | — | CN | disclosed |