Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25035228 | 0.90 | KDM4E (0.40) | KDM4EAKR1B1MAPKAPK2MCHR1TRPA1 | |
| SCHEMBL25036821 | 0.89 | WRN (0.48) | WRNKDM4EAKR1B1MAPTTP53 | |
| SCHEMBL30037511 | 0.89 | WRN (0.48) | WRNKDM4EAKR1B1MAPTTP53 | |
| SCHEMBL31387135 | 0.88 | WRN (0.46) | WRNAKR1B1MAPTLMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL31387155 | 0.88 | WRN (0.46) | WRNAKR1B1MAPTLMNAHSD17B10 | |
| SCHEMBL31384779 | 0.88 | WRN (0.54) | WRNKDM4EKMT2AMAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL31270598 | 0.87 | WRN (0.53) | WRNKDM4EKMT2AMAPTCYP1A2 | |
| SCHEMBL25037077 | 0.86 | MAPT (0.45) | WRNKDM4EKMT2ACA1CA2 | |
| SCHEMBL31394422 | 0.84 | WRN (0.41) | WRNKDM4EKMT2AMAPTMEN1 | |
| SCHEMBL31387138 | 0.84 | WRN (0.42) | WRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255765-A1 | NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) | 2024-12-19 | — | — | WO | disclosed |