Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26059137 | 1.00 | OPRL1 (0.41) | OPRL1RORCJAK2JAK1SETD7 | |
| SCHEMBL30623219 | 1.00 | OPRL1 (0.41) | OPRL1RORCJAK2JAK1SETD7 | |
| SCHEMBL26062015 | 1.00 | OPRL1 (0.41) | OPRL1RORCJAK2JAK1SETD7 | |
| SCHEMBL26057820 | 0.87 | SIGMAR1 (0.41) | JAK2JAK1SETD7KDM1A | |
| SCHEMBL30623264 | 0.87 | SIGMAR1 (0.41) | JAK2JAK1SETD7KDM1A | |
| SCHEMBL31387475 | 0.87 | SIGMAR1 (0.41) | JAK2JAK1SETD7KDM1A | |
| SCHEMBL25433548 | 0.85 | OPRL1 (0.44) | OPRL1RORC | |
| SCHEMBL24346285 | 0.85 | OPRL1 (0.38) | OPRL1RORCGPR119KDM1ATAAR1 | |
| SCHEMBL29413685 | 0.85 | OPRL1 (0.38) | OPRL1RORCGPR119KDM1ATAAR1 | |
| SCHEMBL25359159 | 0.85 | OPRL1 (0.47) | OPRL1RORCTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343353-A | 2-Methyl-4 ',5' -dihydrospiro [ piperidine-4, 7' -thieno [2,3-c ] pyran ] derivatives as APOL1 inhibitors and methods of use thereof | 弗特克斯药品有限公司 | 2025-01-21 | — | — | CN | disclosed |