Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408369 | 1.00 | KDM4E (0.38) | KDM4ELMNAMEN1NPC1RAB9A | |
| SCHEMBL4460942 | 0.88 | CNR2 (0.42) | KDM4ELMNAMEN1NPC1RAB9A | |
| SCHEMBL30704928 | 0.88 | CNR2 (0.42) | KDM4ELMNAMEN1NPC1RAB9A | |
| SCHEMBL16280513 | 0.85 | ESR1 (0.37) | KDM4ELMNAKMT2AESR1ALDH1A1 | |
| SCHEMBL1015406 | 0.83 | MAPK14 (0.40) | KDM4EMEN1KMT2AALDH1A1NTRK1 | |
| SCHEMBL31388014 | 0.83 | MAPK14 (0.40) | KDM4EMEN1KMT2AALDH1A1NTRK1 | |
| SCHEMBL16280160 | 0.82 | ALDH1A1 (0.37) | KDM4EALDH1A1TRPV1GRNSORT1 | |
| SCHEMBL3301591 | 0.80 | CYP1A2 (0.49) | LMNAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL274692 | 0.80 | NPC1 (0.57) | KDM4ELMNAMEN1NPC1RAB9A | |
| SCHEMBL16280069 | 0.77 | SLC6A2 (0.34) | SMN1; SMN2MAPK14CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490458-A | C-3 pyrazole substituted indazole derivative and application thereof | 沈阳药科大学 | 2025-02-21 | — | — | CN | disclosed |
| WO-2025035645-A1 | C-3 PYRAZOLE SUBSTITUTED INDAZOLE DERIVATIVE AND USE THEREOF | 沈阳药科大学 | 2025-02-20 | — | — | WO | disclosed |