SCHEMBL31388215

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(C)C)C(C)C)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.60

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	1/20	0.59

▸	CALCR	P30988	4/20	0.56

▸	SLC6A2	P23975	2/20	0.54

▸	OPRD1	P41143	1/20	0.53

▸	MAPK8	P45983	1/20	0.53

▸	MAPK9	P45984	1/20	0.53

▸	MAPK10	P53779	1/20	0.53

▸	NTSR1	P30989	2/20	0.52

▸	NTSR2	O95665	1/20	0.52

▸	CALCRL	Q16602	1/20	0.52

▸	EP300	Q09472	1/20	0.52

▸	HIF1A	Q16665	1/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31388213	0.99	KEAP1 (0.57)	KEAP1CALCRSLC6A2OPRD1MAPK8
SCHEMBL31388204	0.94	KEAP1 (0.58)	KEAP1CALCRSLC6A2OPRD1CALCRL
SCHEMBL31388233	0.92	KEAP1 (0.60)	KEAP1CALCRSLC6A2OPRD1
SCHEMBL31182731	0.88	CALCR (0.65)	KEAP1CALCROPRD1MAPK8MAPK9
SCHEMBL30504298	0.86	CALCR (0.60)	CALCRSLC6A2OPRD1CALCRLEP300
SCHEMBL30887979	0.86	CALCR (0.65)	KEAP1CALCROPRD1MAPK8MAPK9
SCHEMBL31000906	0.86	CALCR (0.59)	KEAP1CALCROPRD1MAPK8MAPK9
SCHEMBL30831411	0.86	CALCR (0.63)	CALCRMAPK8MAPK9MAPK10
SCHEMBL30429242	0.86	CALCR (0.63)	CALCREP300HIF1A
SCHEMBL30775449	0.86	CALCR (0.58)	KEAP1CALCROPRD1MAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-119161447-A	Long-acting insulin analogue, and preparation method and application thereof	濮阳市旌胜新能源科技有限公司	2024-12-20	—	—	CN	disclosed