Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2072605 | 1.00 | ALOX15 (0.77) | ALOX15LMNAHPGDSMN1; SMN2DHODH | |
| SCHEMBL297225 | 0.87 | ALOX15 (1.00) | ALOX15LMNAHPGDSMN1; SMN2DHODH | |
| SCHEMBL10202005 | 0.86 | ALOX15 (0.79) | ALOX15LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL31389238 | 0.85 | ALOX15 (0.57) | ALOX15LMNASMN1; SMN2KDM4EP2RY12 | |
| SCHEMBL13035843 | 0.85 | ALOX15 (0.73) | ALOX15LMNAHPGDSMN1; SMN2P2RY12 | |
| SCHEMBL27467736 | 0.84 | ALOX15 (0.77) | ALOX15LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL13075989 | 0.84 | ALOX15 (0.77) | ALOX15LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL4409321 | 0.84 | ALOX15 (0.77) | ALOX15LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL6387003 | 0.84 | ALOX15 (0.77) | ALOX15LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL12256861 | 0.84 | ALOX15 (0.77) | ALOX15LMNAHPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |