Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389276 | 0.90 | ALOX15 (0.58) | MEN1KMT2APARP10PARP15ALOX15 | |
| SCHEMBL31389269 | 0.85 | ALOX15 (0.50) | MEN1KMT2APARP10PARP15ALOX15 | |
| SCHEMBL27642217 | 0.84 | ALOX15 (0.50) | PARP10ALOX15GRM2HTT | |
| SCHEMBL31389312 | 0.79 | NR1H4 (0.49) | MEN1KMT2A | |
| SCHEMBL31389245 | 0.79 | GRM2 (0.52) | ALOX15GRM2HTT | |
| SCHEMBL31389311 | 0.79 | GRM2 (0.58) | PARP10GRM2HTT | |
| SCHEMBL31389283 | 0.76 | NR4A2 (0.46) | ALOX15GRM2 | |
| SCHEMBL4740261 | 0.76 | ALOX15 (0.60) | ALOX15ALDH1A1 | |
| SCHEMBL13075989 | 0.76 | ALOX15 (0.77) | ALOX15GRM2ALDH1A1HTT | |
| SCHEMBL9380171 | 0.75 | ALOX15 (0.46) | ALOX15GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |