Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21315317 | 0.87 | KMT2A (0.40) | KMT2ACYP1A2MAPTGAATP53 | |
| SCHEMBL31389838 | 0.80 | KMT2A (0.38) | KMT2ACYP1A2MAPTGAATP53 | |
| SCHEMBL3549149 | 0.77 | CYP1A2 (0.40) | KMT2ACYP1A2MAPTGAAADORA3 | |
| SCHEMBL2929174 | 0.77 | NPC1 (0.41) | KMT2ACYP1A2GAAKDM4E | |
| SCHEMBL19284286 | 0.76 | KMT2A (0.38) | KMT2ACYP1A2MAPTGAATP53 | |
| SCHEMBL2928372 | 0.76 | NPC1 (0.43) | KMT2ACYP1A2KDM4E | |
| SCHEMBL26726779 | 0.75 | KDM4E (0.42) | KMT2ACYP1A2GAAADORA3KDM4E | |
| SCHEMBL6379433 | 0.75 | NPC1 (0.44) | KMT2AGAAKDM4E | |
| SCHEMBL30836782 | 0.74 | KMT2A (0.40) | KMT2ACYP1A2MAPTGAATP53 | |
| SCHEMBL3542014 | 0.74 | CYP1A2 (0.39) | KMT2ACYP1A2MAPTGAAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |