Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389817 | 0.78 | IDH1 (0.33) | — | |
| SCHEMBL31059662 | 0.75 | NPC1 (0.30) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29072222 | 0.73 | — | — | |
| SCHEMBL29072224 | 0.73 | — | — | |
| SCHEMBL12208788 | 0.72 | MET (0.36) | — | |
| SCHEMBL31389482 | 0.71 | NPC1 (0.37) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31389512 | 0.71 | KDM4E (0.32) | SMN1; SMN2 | |
| SCHEMBL31389648 | 0.70 | — | — | |
| SCHEMBL31389821 | 0.69 | MET (0.37) | — | |
| SCHEMBL744190 | 0.69 | MET (0.35) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |