Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21827249 | 0.93 | HPGD (0.54) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL21827247 | 0.93 | HPGD (0.54) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL23708985 | 0.80 | HPGD (0.61) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL22875029 | 0.80 | HPGD (0.83) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL23708986 | 0.80 | HPGD (0.61) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL3426748 | 0.80 | HPGD (0.61) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL26159934 | 0.78 | HTT (0.56) | HPGDALDH1A1TSHRHSD11B1LMNA | |
| SCHEMBL27287509 | 0.78 | SMN1; SMN2 (0.50) | HPGDALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL16512804 | 0.78 | HPGD (0.65) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL20186941 | 0.78 | HPGD (1.00) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |