Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.60 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.60 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3504308 | 1.00 | HPGD (1.00) | HPGDALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL19612780 | 1.00 | HPGD (1.00) | HPGDALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL16992039 | 1.00 | HPGD (1.00) | HPGDALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL18228450 | 1.00 | HPGD (1.00) | HPGDALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL806748 | 0.97 | HPGD (0.95) | HPGDALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL19658219 | 0.97 | HPGD (0.95) | HPGDALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL3695372 | 0.92 | ALDH1A1 (0.86) | HPGDALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL12714626 | 0.92 | HPGD (0.86) | HPGDALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL2386976 | 0.92 | ALDH1A1 (0.86) | HPGDALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL1826063 | 0.92 | ALDH1A1 (0.86) | HPGDALDH1A1TSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148429-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | SELVITA S.A. (PL) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148429-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | BRCA1, NQO2, NQO1 | HPGD 87/4885ALDH1A1 1674/4885TSHR 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.