Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389983 | 0.85 | POLB (0.41) | POLBSMN1; SMN2MAPTALDH1A1CYP2D6 | |
| Bicarbonate SCHEMBL31389668 | 0.84 | POLB (0.40) | POLBSMN1; SMN2MAPTALDH1A1CYP2D6 | |
| SCHEMBL31389804 | 0.81 | POLB (0.58) | POLBPTPN2PTPN1SMN1; SMN2MAPT | |
| SCHEMBL31389410 | 0.76 | POLB (0.58) | POLBPTPN2PTPN1SMN1; SMN2MAPT | |
| SCHEMBL743845 | 0.74 | POLB (1.00) | POLBPTPN2PTPN1SMN1; SMN2MAPT | |
| SCHEMBL26925068 | 0.73 | POLB (0.65) | POLBPTPN2PTPN1SMN1; SMN2MAPT | |
| SCHEMBL23086434 | 0.72 | POLB (0.77) | POLBPTPN2PTPN1SMN1; SMN2MAPT | |
| SCHEMBL23086437 | 0.72 | POLB (0.77) | POLBPTPN2PTPN1SMN1; SMN2MAPT | |
| SCHEMBL3977630 | 0.72 | POLB (0.90) | POLBPTPN2PTPN1SMN1; SMN2MAPT | |
| SCHEMBL23086436 | 0.72 | POLB (0.77) | POLBPTPN2PTPN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |