Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30357078 | 0.82 | KMT2A (0.41) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL31389929 | 0.76 | LRRK2 (0.34) | LRRK2LMNACYP2C9 | |
| SCHEMBL19716145 | 0.73 | MEN1 (0.56) | LRRK2LMNACYP2C9MEN1ALDH1A1 | |
| SCHEMBL31389987 | 0.72 | LRRK2 (0.43) | LRRK2MEN1ALDH1A1MAPTPKM | |
| SCHEMBL31389549 | 0.72 | PDE9A (0.30) | — | |
| SCHEMBL31389402 | 0.70 | KDM4E (0.35) | LRRK2LMNACYP2C9OPRL1MEN1 | |
| SCHEMBL19728273 | 0.68 | GAA (0.32) | ALDH1A1 | |
| SCHEMBL19728276 | 0.68 | GAA (0.32) | ALDH1A1 | |
| SCHEMBL19728272 | 0.68 | GAA (0.32) | ALDH1A1 | |
| SCHEMBL19239549 | 0.67 | GAA (0.34) | MEN1ALDH1A1MAPTPKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |