Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21577454 | 0.83 | ALDH1A1 (0.43) | KDM4EHTTALDH1A1MEN1MAPT | |
| SCHEMBL21577448 | 0.81 | ALDH1A1 (0.38) | KDM4EHTTALDH1A1MEN1MAPT | |
| SCHEMBL21577447 | 0.81 | ALDH1A1 (0.38) | KDM4EHTTALDH1A1MEN1MAPT | |
| SCHEMBL21577452 | 0.81 | ALDH1A1 (0.38) | KDM4EHTTALDH1A1MEN1MAPT | |
| SCHEMBL4954571 | 0.76 | ALDH1A1 (0.42) | KDM4EHTTALDH1A1MEN1MAPT | |
| SCHEMBL19716145 | 0.74 | MEN1 (0.56) | KDM4EALDH1A1MEN1MAPTPKM | |
| SCHEMBL31389987 | 0.74 | LRRK2 (0.43) | ALDH1A1MEN1MAPTPKMALOX15 | |
| SCHEMBL31389512 | 0.72 | KDM4E (0.32) | KDM4EHTTGAASMN1; SMN2 | |
| SCHEMBL31389747 | 0.70 | LRRK2 (0.36) | ALDH1A1MEN1MAPTPKMALOX15 | |
| SCHEMBL27148379 | 0.70 | ALDH1A1 (0.37) | KDM4EHTTALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |