Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14008901 | 0.79 | HRH4 (0.38) | HRH4SMPD3L3MBTL1MAPT | |
| SCHEMBL20220763 | 0.78 | HRH4 (0.34) | HRH4SMPD3 | |
| SCHEMBL19012501 | 0.78 | HRH4 (0.37) | HRH4SMPD3L3MBTL1MAPT | |
| SCHEMBL22487889 | 0.75 | HRH4 (0.35) | HRH4SMPD3L3MBTL1KDM4EMAPT | |
| SCHEMBL5644866 | 0.75 | CSNK2A1 (0.31) | CSNK2A1NPSR1CSNK2A2CSNK2B | |
| SCHEMBL22487932 | 0.73 | HRH4 (0.35) | HRH4SMPD3 | |
| SCHEMBL7326945 | 0.73 | TNKS (0.56) | TNKSPARP1WNT3ATNKS2SMN1; SMN2 | |
| SCHEMBL22487904 | 0.69 | HRH4 (0.32) | HRH4SMPD3 | |
| SCHEMBL22487915 | 0.67 | HRH4 (0.31) | HRH4SMPD3HPGD | |
| SCHEMBL2254884 | 0.67 | HRH4 (0.38) | HRH4SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |