Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22487904 | 0.96 | HRH4 (0.32) | HRH4SMPD3 | |
| SCHEMBL22487915 | 0.83 | HRH4 (0.31) | HRH4SMPD3 | |
| SCHEMBL14008901 | 0.81 | HRH4 (0.38) | HRH4SMPD3 | |
| SCHEMBL19012501 | 0.79 | HRH4 (0.37) | HRH4SMPD3 | |
| SCHEMBL22487889 | 0.77 | HRH4 (0.35) | HRH4SMPD3 | |
| SCHEMBL31389798 | 0.73 | HRH4 (0.35) | HRH4SMPD3 | |
| SCHEMBL20220763 | 0.72 | HRH4 (0.34) | HRH4SMPD3 | |
| SCHEMBL9178197 | 0.69 | HRH4 (0.38) | HRH4SMPD3 | |
| SCHEMBL22858756 | 0.67 | HRH4 (0.36) | HRH4SMPD3 | |
| SCHEMBL171272 | 0.66 | HAVCR2 (0.48) | HRH4SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308165-A1 | Compounds as Ras Inhibitors and Use Thereof | D. E. SHAW RESEARCH, LLC | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308165-A1 | Compounds as Ras Inhibitors and Use Thereof | KRAS, NRAS, HRAS | HRH4 1445/4885SMPD3 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.