SCHEMBL31390397

SCHEMBL31390397

CC(C)(C[C@](O)(CNc1cccc2cnccc12)C(F)(F)F)c1cc(F)cc2c1OCC2

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 20/20 0.59
PGR P06401 12/20 0.59
NR3C2 P08235 12/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3759200 1.00 NR3C1 (0.59) NR3C1PGRNR3C2
SCHEMBL3757358 1.00 NR3C1 (0.59) NR3C1PGRNR3C2
SCHEMBL31390401 1.00 NR3C1 (0.59) NR3C1PGRNR3C2
SCHEMBL292584 1.00 NR3C1 (0.59) NR3C1PGRNR3C2
SCHEMBL31390424 1.00 NR3C1 (0.59) NR3C1PGRNR3C2
SCHEMBL12755287 0.90 NR3C1 (0.67) NR3C1PGRNR3C2
SCHEMBL12551705 0.88 NR3C1 (0.55) NR3C1PGRNR3C2
SCHEMBL3775475 0.85 NR3C1 (0.53) NR3C1PGRNR3C2
SCHEMBL31390399 0.85 NR3C1 (0.53) NR3C1PGRNR3C2
SCHEMBL31390427 0.85 NR3C1 (0.53) NR3C1PGRNR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113382730-B Selective glucocorticoid receptor modifier for use in the treatment of impaired skin wound healing 阿克里斯生物医药有限公司 2025-02-25 CN disclosed