SCHEMBL31390403

SCHEMBL31390403

CC(C)(C[C@](O)(CNc1cccc2c(=O)[nH]ccc12)C(F)(F)F)c1cc(F)cc2c1OCC2

nearest known ligand 0.64

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 19/20 0.64
PGR P06401 13/20 0.64
NR3C2 P08235 12/20 0.51
PARP1 P09874 1/20 0.38
AR P10275 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL450445 1.00 NR3C1 (0.64) NR3C1PGRNR3C2PARP1AR
SCHEMBL31390418 1.00 NR3C1 (0.64) NR3C1PGRNR3C2PARP1AR
SCHEMBL31390394 1.00 NR3C1 (0.64) NR3C1PGRNR3C2PARP1AR
SCHEMBL12755287 0.86 NR3C1 (0.67) NR3C1PGRNR3C2
SCHEMBL292036 0.85 NR3C1 (0.49) NR3C1PGRNR3C2AR
SCHEMBL30874745 0.85 NR3C1 (0.49) NR3C1PGRNR3C2AR
SCHEMBL31390415 0.85 NR3C1 (0.57) NR3C1PGRNR3C2
SCHEMBL293852 0.85 NR3C1 (0.57) NR3C1PGRNR3C2
SCHEMBL31390423 0.85 NR3C1 (0.57) NR3C1PGRNR3C2
SCHEMBL31390413 0.85 NR3C1 (0.57) NR3C1PGRNR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113382730-B Selective glucocorticoid receptor modifier for use in the treatment of impaired skin wound healing 阿克里斯生物医药有限公司 2025-02-25 CN disclosed