Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484978 | 0.85 | POLB (0.48) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL30817323 | 0.84 | CRBN (0.54) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL31355819 | 0.84 | CRBN (0.42) | CRBNDDB1POLBGSPT1LMNA | |
| SCHEMBL31390652 | 0.84 | CRBN (0.48) | CRBNDDB1POLBGSPT1LMNA | |
| SCHEMBL31355988 | 0.83 | CRBN (0.42) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24881104 | 0.83 | CRBN (0.45) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL30817371 | 0.81 | CRBN (0.56) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL28969661 | 0.81 | CRBN (0.69) | CRBNDDB1POLBLMNAMAPT | |
| SCHEMBL31356139 | 0.81 | CRBN (0.52) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL31355844 | 0.81 | CRBN (0.47) | CRBNDDB1POLBGSPT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504710-A | PROTACs compound for targeted degradation of PRMT5 and application thereof | 昆明医科大学 | 2025-02-25 | — | — | CN | disclosed |