Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31355893 | 0.87 | CRBN (0.48) | CRBNDDB1LMNAKDM4ECXCR4 | |
| SCHEMBL31355803 | 0.87 | CRBN (0.43) | CRBNDDB1POLBGSPT1LMNA | |
| SCHEMBL31485103 | 0.85 | KMT2A (0.47) | CRBNDDB1GSPT1 | |
| SCHEMBL31355990 | 0.84 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL31355862 | 0.82 | CRBN (0.45) | CRBNDDB1POLBGSPT1HRH3 | |
| SCHEMBL31355967 | 0.82 | CRBN (0.45) | CRBNDDB1POLBGSPT1HRH3 | |
| SCHEMBL25501588 | 0.81 | CRBN (0.57) | CRBNDDB1POLBGSPT1LMNA | |
| SCHEMBL30817323 | 0.81 | CRBN (0.54) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL31390654 | 0.81 | CRBN (0.50) | CRBNDDB1POLBGSPT1LMNA | |
| SCHEMBL31356139 | 0.80 | CRBN (0.52) | CRBNDDB1POLBGSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119768392-A | Aryl or heteroaryl substituted glutarimide derivatives and uses thereof | 标新生物医药科技(上海)有限公司 | 2025-04-04 | — | — | CN | claimed |
| WO-2025026422-A1 | ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2025-02-06 | — | — | WO | claimed |