Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30738805 | 0.87 | ALDH1A1 (0.37) | ALDH1A1MAPTHTTTP53LMNA | |
| SCHEMBL27178666 | 0.86 | MAPT (0.42) | ALDH1A1MAPTNPSR1HTTTP53 | |
| SCHEMBL27270132 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL27267291 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTNPSR1HTTLMNA | |
| SCHEMBL2829001 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTNPSR1HTTTP53 | |
| SCHEMBL30369746 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTNPSR1HTTTP53 | |
| SCHEMBL18157850 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTNPSR1HTTTP53 | |
| SCHEMBL31392992 | 0.81 | NR1H2 (0.36) | KMT2A | |
| SCHEMBL3932150 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAL3MBTL1GAA | |
| SCHEMBL2829002 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTHTTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727943-A1 | INHIBITORS OF MET KINASE | Celyn Therapeutics, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024259060-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2024-12-19 | — | — | WO | disclosed |