SCHEMBL3139344

SCHEMBL3139344

C=CC(O)OP(=O)(OC(O)C=C)OC(O)C=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30569 0.83
SCHEMBL29171272 0.81 FDPS (0.32)
SCHEMBL8850158 0.79
SCHEMBL8850161 0.77
Hypophosphorous Acid SCHEMBL7155853 0.75
SCHEMBL7122407 0.74
SCHEMBL11785154 0.73
SCHEMBL28101877 0.72
SCHEMBL7122410 0.72 MPI (0.31)
SCHEMBL29171265 0.69 PPARD (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102525832-B Polyglyceryl compounds and compositions JOHNSON & JOHNSON CONSUMER COMPANIES (US) 2016-06-01 CN claimed
CN-102525832-A Polyglyceryl compounds and compositions JOHNSON & JOHNSON CONSUMER 2012-07-04 CN claimed
US-20090221386-A1 GOLF BALL WITH INTERMEDIATE LAYER CONTAINING AN EXPANDABLE POLYMER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-09-03 US claimed
EP-0807624-B1 RETINOIC ACID DERIVATIVES SALK INST FOR BIOLOGICAL STUDI (US) 2009-08-12 EP claimed
US-20060234812-A1 Golf ball with intermediate layer containing an expandable polymer ACUSHNET COMPANY 2006-10-19 US claimed
CN-1711313-A Flame retardant compositions CIBA SC HOLDING AG (CH) 2005-12-21 CN claimed
US-20030105166-A1 Controlling cell differentiation EISAI INC. 2003-06-05 US claimed
US-6506917-B1 Ligands which are more selective for retinoid X receptor than is retinoic acid THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2003-01-14 US claimed
US-5968989-A ADMINISTERING PHARMACEUTICAL COMPOSITION COMPRISING A COMPOUND MORE POTENT AS A MODULATOR FOR RETINOID X RECEPTOR (RXR) IN A COTRANSFECTION ASSAY THAN IS ALL-TRANS-RETINOIC ACID, AND A CARRIER; SKIN DISORDERS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1999-10-19 US claimed
US-5763462-A 1,1-DIMETHYL-4,4'-DIPYRIDIUM DICHLORIDE HERBICIDE WITH ORGANIC PHOSPHATE ACTIVATOR KAO CORPORATION (JP) 1998-06-09 US claimed
EP-0617614-B1 MEANS FOR THE MODULATION OF PROCESSES MEDIATED BY RETINOID RECEPTORS AND COMPOUNDS USEFUL THEREFOR SALK INST FOR BIOLOGICAL STUDI (US) 1998-03-04 EP claimed
EP-0807624-A2 Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1997-11-19 EP claimed
US-5656616-A ORGANIC PHOSPHATE COMPOUND KAO CORPORATION (JP) 1997-08-12 US claimed
US-5654291-A AGRICULTURAL INSECTICIDE COMPOSITION INCLUDING MONOESTER OF PHOSPHORIC ACID TO INCREASE INSECTICIDAL RATE KAO CORPORATION (JP) 1997-08-05 US claimed
US-5627167-A 2-CHLORO-2*,6*-DIETHYL-N-(METHOXYMETHYL)ACETANILIDE WITH ALKYL PHOSPHATE PROMOTERS KAO CORPORATION (JP) 1997-05-06 US claimed
US-5627166-A Activator for acaracide KAO CORPORATION (JP) 1997-05-06 US claimed
US-5618802-A PHOSPHATE OR PHOSPHATE SALT KAO CORPORATION (JP) 1997-04-08 US claimed
US-5612322-A N-(PHOSPHONOMETHYL) GLYCINE, ORGANOPHOSPHATE KAO CORPORATION (JP) 1997-03-18 US claimed
EP-0173563-B1 SUPERSENSITIZATION OF SILVER HALIDE EMULSIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-05 EP claimed
WO-2024135543-A1 COMPOSITION COMPRISING MODIFIED STARCH, C13-C15 FATTY ACID, AND POWDERY ORGANIC SALT L'OREAL (FR) 2024-06-27 WO disclosed
US-20230348522-A1 METHOD FOR PRODUCING BICYCLIC PHOSPHORAMIDITE DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-11-02 US disclosed
CN-116981772-A Nucleic acid pharmaceuticals expressing splice variants of myostatin 神户天然物化学株式会社 2023-10-31 CN disclosed
WO-2023176863-A1 CHEMICALLY-MODIFIED OLIGONUCLEOTIDE HAVING RNAI ACTIVITY 第一三共株式会社 2023-09-21 WO disclosed
WO-2023176862-A1 siRNA FOR SUPPRESSING EXPRESSION OF TRANSFERRIN RECEPTOR-2 第一三共株式会社 2023-09-21 WO disclosed
CN-115976028-A Remedies for glycogen disease type Ia 第一三共株式会社 2023-04-18 CN disclosed
CN-114176077-B Barrel-mixed spraying aid containing rhamnolipid and preparation method and application thereof 中化化工科学技术研究总院有限公司 2023-04-07 CN disclosed
CN-115916976-A Antisense nucleic acid for inducing exon skipping of angiotensin converting enzyme 2 gene 神户天然物化学株式会社 2023-04-04 CN disclosed
CN-115793287-A Reduction method, reduction effect detection method and reduction instrument for daily-cast corneal contact lens 苏州三个臭皮匠生物科技有限公司 2023-03-14 CN disclosed
EP-4029520-A1 GALNAC-OLIGONUCLEOTIDE CONJUGATE FOR LIVER-TARGETED DELIVERY USE, AND METHOD FOR PRODUCING SAME Daiichi Sankyo Company, Limited (JP) 2022-07-20 EP disclosed
CN-114616332-A GalNAc-oligonucleotide conjugates for delivery to liver and methods of making the same 第一三共株式会社 2022-06-10 CN disclosed
CN-114502565-A Process for producing bicyclic phosphoramidites 第一三共株式会社 2022-05-13 CN disclosed
CN-114176077-A Barrel-mixed spraying aid containing rhamnolipid and preparation method and application thereof 中化化工科学技术研究总院有限公司 2022-03-15 CN disclosed
CN-114080238-A Nucleic acid drug for inhibiting production of mRNA of myostatin gene 神户天然物化学株式会社 2022-02-22 CN disclosed
CN-114026234-A Antisense oligonucleotides altering DUX4pre-mRNA splicing 第一三共株式会社 2022-02-08 CN disclosed
WO-2021075538-A1 METHOD FOR PRODUCING BICYCLIC PHOSPHORAMIDITE 第一三共株式会社 2021-04-22 WO disclosed
WO-2021049504-A1 GALNAC-OLIGONUCLEOTIDE CONJUGATE FOR LIVER-TARGETED DELIVERY USE, AND METHOD FOR PRODUCING SAME 第一三共株式会社 2021-03-18 WO disclosed
EP-3765849-A1 DETERMINATION SYSTEM, COMPUTING DEVICE, DETERMINATION METHOD, AND PROGRAM Menicon Co., Ltd. (JP) 2021-01-20 EP disclosed
EP-3764879-A1 SYSTEM FOR COLLECTING AND UTILIZING HEALTH DATA Menicon Co., Ltd. (JP) 2021-01-20 EP disclosed
US-20210007643-A1 SYSTEM FOR COLLECTING AND UTILIZING HEALTH DATA MENICON CO., LTD. (JP) 2021-01-14 US disclosed
US-20210007670-A1 DETERMINATION SYSTEM, COMPUTING DEVICE, DETERMINATION METHOD, AND PROGRAM MENICON CO LTD (JP) 2021-01-14 US disclosed
CN-112218950-A Therapeutic agent for myocardial damage 第一三共株式会社 2021-01-12 CN disclosed
CN-106893040-B Aqueous multistage emulsion copolymer composition for joint applications 罗门哈斯公司 2020-11-10 CN disclosed
CN-111511915-A Remedies for glycogen disease type Ia 第一三共株式会社 2020-08-07 CN disclosed
CN-111225653-A Compact aerosol hair care compositions comprising hydrocarbon blowing agents 宝洁公司 2020-06-02 CN disclosed
CN-111225654-A Compact aerosol hair care compositions comprising hydrocarbon blowing agents 宝洁公司 2020-06-02 CN disclosed
WO-2019176952-A1 Determination System, Computing Device, Determination Method, and Program MENICON CO., LTD. (JP) 2019-09-19 WO disclosed
WO-2019175660-A1 METHOD FOR DETECTING A HEALTH CONDITION WITH BIOMARKERS MENICON CO. LTD. (JP) 2019-09-19 WO disclosed
WO-2019175663-A1 METHOD FOR GENERATING A CONTACT LENS RECOMMENDATION MENICON CO. LTD. (JP) 2019-09-19 WO disclosed
US-20190281936-A1 CONTACT LENS CONTAINER WITH BIOMARKER DETECTION MENICON CO., LTD. (JP) 2019-09-19 US disclosed
WO-2019175669-A1 SYSTEM FOR COLLECTING AND UTILIZING HEALTH DATA MENICON CO. LTD. (JP) 2019-09-19 WO disclosed
WO-2019172286-A1 THERAPEUTIC AGENT FOR GLYCOGEN STORAGE DISEASE TYPE IA 第一三共株式会社 2019-09-12 WO disclosed
CN-109789070-A Aerosol hair care composition comprising HFO foaming agent and water-miscible solvent 宝洁公司 2019-05-21 CN disclosed
CN-108024935-A COMPOSITIONS COMPRISING ZWITTERIONIC ALKYL-ALKANOYLAMIDES and/or ALKYL ALKANOATES 强生消费者公司 2018-05-11 CN disclosed
CN-107519031-A Personal care compositions containing complex polyelectrolytes 强生消费者公司 2017-12-29 CN disclosed
CN-107519040-A Clarify the personal care cleansing compositions to suspend 强生消费者公司 2017-12-29 CN disclosed
CN-107072907-A Include the composition of amphion ester aminoalkanoates 强生消费者公司 2017-08-18 CN disclosed
CN-106880515-A Cleaning rod comprising polyglycerol ester 强生消费者公司 2017-06-23 CN disclosed
CN-102558541-B Polyglyceryl compounds and compositions 强生消费者公司 2016-09-28 CN disclosed
CN-103172526-B Cationic polyglyceryl composition and compound 强生消费者公司 2016-08-17 CN disclosed
CN-102532510-B polyglyceryl compounds and compositions 强生消费者公司 2016-08-03 CN disclosed
CN-103172609-B Cationic polyglyceryl compositions and compound 强生消费者公司 2016-06-08 CN disclosed
CN-102525832-B Polyglyceryl compounds and compositions JOHNSON & JOHNSON CONSUMER COMPANIES (US) 2016-06-01 CN disclosed
CN-102525843-B Polyglyceryl compounds and composition JOHNSON & JOHNSON CONSUMER COMPANIES (US) 2016-05-11 CN disclosed
CN-102552063-B Containing the compositions of polyglyceryl non-ionic surface active agent JOHNSON & JOHNSON CONSUMER COMPANIES (US) 2016-02-24 CN disclosed
CN-105263470-A Cleansing bars comprising superhydrophilic amphiphilic copolymers and methods of use thereof JOHNSO & JOHNSON CONSUMER COMPANIES INC 2016-01-20 CN disclosed
CN-103415528-A Condensation products of melamine and phenylphosphonic acid and their use as flame retardants BASF SE 2013-11-27 CN disclosed
CN-102149762-B Flame retardant compositions with polymeric dispersing agents BASF SE 2013-07-31 CN disclosed
CN-102834445-A Flame retardant compositions of phosphinate and nitroxyl derivatives BASF SE 2012-12-19 CN disclosed
CN-102712668-A Phosphorus-substituted alkoxyamine compounds BASF SE 2012-10-03 CN disclosed
CN-102552063-A Compositions comprising polyglyceryl nonionic surfactants JOHNSON & JOHNSON CONSUMER 2012-07-11 CN disclosed
CN-102525843-A Polyglyceryl compounds and compositions JOHNSON & JOHNSON CONSUMER 2012-07-04 CN disclosed
CN-102525832-A Polyglyceryl compounds and compositions JOHNSON & JOHNSON CONSUMER 2012-07-04 CN disclosed
CN-101278001-B Polyurethane flame retardant compositions CIBA HOLDING INC 2012-07-04 CN disclosed
CN-1927900-B Ellipsoidal organic polymer particles and process for producing the same NISSHIN SPINNING 2012-04-18 CN disclosed
CN-102149762-A Flame retardant compositions with polymeric dispersing agents BASF SE 2011-08-10 CN disclosed
US-20100292031-A1 GOLF BALL WITH INTERMEDIATE LAYER CONTAINING AN EXPANDABLE POLYMER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2010-11-18 US disclosed
US-7785217-B2 Golf ball with intermediate layer containing an expandable polymer ACUSHNET COMPANY (US) 2010-08-31 US disclosed
US-20090221386-A1 GOLF BALL WITH INTERMEDIATE LAYER CONTAINING AN EXPANDABLE POLYMER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-09-03 US disclosed
EP-0807624-B1 RETINOIC ACID DERIVATIVES SALK INST FOR BIOLOGICAL STUDI (US) 2009-08-12 EP disclosed
US-7549936-B2 Golf ball with intermediate layer containing an expandable polymer ACUSHNET COMPANY (US) 2009-06-23 US disclosed
CN-101278001-A Polyurethane flame retardant compositions CIBA HOLDING INC (CH) 2008-10-01 CN disclosed
CN-100387645-C Flame retardant composition CIBA SC HOLDING AG (CH) 2008-05-14 CN disclosed
CN-100384820-C Phosphate prodrugs of fluorooxindoles BRISTOL MYERS SQUIBB CO (US) 2008-04-30 CN disclosed
EP-1485085-A4 PHOSPHATE PRODRUGS OF FLUOROOXINDOLES BRISTOL MYERS SQUIBB CO (US) 2007-03-14 EP disclosed
CN-1927900-A Oval-spherical organic polymer particles and method of production NISSHIN SPINNING (JP) 2007-03-14 CN disclosed
US-20060234812-A1 Golf ball with intermediate layer containing an expandable polymer ACUSHNET COMPANY 2006-10-19 US disclosed
US-20060211768-A1 Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2006-09-21 US disclosed
CN-1791435-A Method and composition for reducing contact lens swelling BAUSCH & LOMB (US) 2006-06-21 CN disclosed
US-7056954-B2 Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2006-06-06 US disclosed
US-6992108-B1 Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2006-01-31 US disclosed
CN-1711313-A Flame retardant compositions CIBA SC HOLDING AG (CH) 2005-12-21 CN disclosed
US-6930100-B2 Phosphate prodrugs of fluoroxindoles BRISTOL-MYERS SQUIBB COMPANY (US) 2005-08-16 US disclosed
CN-1652769-A Phosphate prodrugs of fluorooxindoles BRISTOL MYERS SQUIBB CO (US) 2005-08-10 CN disclosed
WO-2005051960-A2 HYDROCARBYL AMINOHYDROCARBONOATES AND AMINOHYDROCARBONOL HYDROCARBONOATES AS ANTIMICROBIAL AND ANTIVIRAL AGENTS MIDWEST RESEARCH LABORATORIES, LLC (US) 2005-06-09 WO disclosed
US-20050113274-A1 Hydrocarbyl aminohydrocarbonoates and aminohydrocarbonol hydrocarbonoates as antimicrobial and antiviral agents MIDWEST RESEARCH LABORATORIES, LLC 2005-05-26 US disclosed
EP-1485085-A1 PHOSPHATE PRODRUGS OF FLUOROOXINDOLES Bristol-Myers Squibb Company (US) 2004-12-15 EP disclosed
US-20040006144-A1 Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2004-01-08 US disclosed
US-20030195169-A1 Phosphate prodrugs of fluorooxindoles BRISTOL-MYERS SQUIBB COMPANY 2003-10-16 US disclosed
WO-2003080047-A1 PHOSPHATE PRODRUGS OF FLUOROOXINDOLES BRISTOL-MYERS SQUIBB COMPANY (US) 2003-10-02 WO disclosed
US-6576676-B1 9-phenyl-9-cis-retinoic acid; high affinity and specificity THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2003-06-10 US disclosed
US-20030105166-A1 Controlling cell differentiation EISAI INC. 2003-06-05 US disclosed
US-6506917-B1 Ligands which are more selective for retinoid X receptor than is retinoic acid THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2003-01-14 US disclosed
US-6190574-B1 OIL ADDITIVE KAO CORPORATION (JP) 2001-02-20 US disclosed
US-5968989-A ADMINISTERING PHARMACEUTICAL COMPOSITION COMPRISING A COMPOUND MORE POTENT AS A MODULATOR FOR RETINOID X RECEPTOR (RXR) IN A COTRANSFECTION ASSAY THAN IS ALL-TRANS-RETINOIC ACID, AND A CARRIER; SKIN DISORDERS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1999-10-19 US disclosed
US-5932622-A PREVENTION WRINKLING, ACNE; ANTITUMOR AGENT THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1999-08-03 US disclosed
US-5763462-A 1,1-DIMETHYL-4,4'-DIPYRIDIUM DICHLORIDE HERBICIDE WITH ORGANIC PHOSPHATE ACTIVATOR KAO CORPORATION (JP) 1998-06-09 US disclosed
US-5763462-A 1,1-DIMETHYL-4,4'-DIPYRIDIUM DICHLORIDE HERBICIDE WITH ORGANIC PHOSPHATE ACTIVATOR KAO CORPORATION (JP) 1998-06-09 US disclosed
EP-0617614-B1 MEANS FOR THE MODULATION OF PROCESSES MEDIATED BY RETINOID RECEPTORS AND COMPOUNDS USEFUL THEREFOR SALK INST FOR BIOLOGICAL STUDI (US) 1998-03-04 EP disclosed
EP-0807624-A2 Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1997-11-19 EP disclosed
US-5656616-A ORGANIC PHOSPHATE COMPOUND KAO CORPORATION (JP) 1997-08-12 US disclosed
US-5656616-A ORGANIC PHOSPHATE COMPOUND KAO CORPORATION (JP) 1997-08-12 US disclosed
US-5654291-A AGRICULTURAL INSECTICIDE COMPOSITION INCLUDING MONOESTER OF PHOSPHORIC ACID TO INCREASE INSECTICIDAL RATE KAO CORPORATION (JP) 1997-08-05 US disclosed
US-5654291-A AGRICULTURAL INSECTICIDE COMPOSITION INCLUDING MONOESTER OF PHOSPHORIC ACID TO INCREASE INSECTICIDAL RATE KAO CORPORATION (JP) 1997-08-05 US disclosed
US-5627167-A 2-CHLORO-2*,6*-DIETHYL-N-(METHOXYMETHYL)ACETANILIDE WITH ALKYL PHOSPHATE PROMOTERS KAO CORPORATION (JP) 1997-05-06 US disclosed
US-5627167-A 2-CHLORO-2*,6*-DIETHYL-N-(METHOXYMETHYL)ACETANILIDE WITH ALKYL PHOSPHATE PROMOTERS KAO CORPORATION (JP) 1997-05-06 US disclosed
US-5627166-A Activator for acaracide KAO CORPORATION (JP) 1997-05-06 US disclosed
US-5627166-A Activator for acaracide KAO CORPORATION (JP) 1997-05-06 US disclosed
US-5618802-A PHOSPHATE OR PHOSPHATE SALT KAO CORPORATION (JP) 1997-04-08 US disclosed
US-5618802-A PHOSPHATE OR PHOSPHATE SALT KAO CORPORATION (JP) 1997-04-08 US disclosed
US-5612322-A N-(PHOSPHONOMETHYL) GLYCINE, ORGANOPHOSPHATE KAO CORPORATION (JP) 1997-03-18 US disclosed
US-5612322-A N-(PHOSPHONOMETHYL) GLYCINE, ORGANOPHOSPHATE KAO CORPORATION (JP) 1997-03-18 US disclosed
US-5198012-A Compositions with phosphate derivatives KAO CORPORATION (JP) 1993-03-30 US disclosed
US-5198012-A Compositions with phosphate derivatives KAO CORPORATION (JP) 1993-03-30 US disclosed
US-5043008-A Polyoxyalkylene alkyl ether phosphate KAO CORPORATION (JP) 1991-08-27 US disclosed
US-5043008-A Polyoxyalkylene alkyl ether phosphate KAO CORPORATION (JP) 1991-08-27 US disclosed
US-4976769-A USING POLYOXYALKYLENE ETHER PHOSPHATE KAO CORPORATION (JP) 1990-12-11 US disclosed
US-4510070-A HYDROXYALKYL PHOSPHATES AS OLEOPHILIC EMULSIFIERS; COSMETICS; SKINSENSITIVITY KAO CORPORATION (JP) 1985-04-09 US disclosed
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US disclosed
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US disclosed