Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 19/20 | 0.44 |
| ▸ | KDM6B | O15054 | 7/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422394 | 0.78 | ALDH1A1 (0.42) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6634100 | 0.76 | AURKA (0.36) | TDP1 | |
| SCHEMBL28533895 | 0.75 | KDM4C (0.47) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL23088082 | 0.75 | CCNC (0.50) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL19329111 | 0.75 | TSHR (0.41) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL23088081 | 0.75 | CCNC (0.50) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL19329109 | 0.75 | TSHR (0.41) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9000522 | 0.74 | KDM4C (0.50) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL31165744 | 0.74 | KDM4C (0.46) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL21056630 | 0.73 | CYP11B1 (0.52) | KDM4CKDM6BKDM4DKDM4EKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |