Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23147036 | 0.85 | KDM4E (0.44) | KDM4EKMT2AP2RX3ALDH1A1HTT | |
| SCHEMBL21393836 | 0.81 | KDM4E (0.44) | KDM4EKMT2AALDH1A1HTTPDE10A | |
| SCHEMBL29150280 | 0.78 | KDM4E (0.46) | KDM4EKMT2AALDH1A1HTTPDE10A | |
| SCHEMBL11562679 | 0.78 | KDM4E (0.65) | KDM4EKMT2AP2RX3ALDH1A1PDE10A | |
| SCHEMBL15322103 | 0.74 | KDM4E (0.42) | KDM4EKMT2AP2RX3ALDH1A1HTT | |
| SCHEMBL195230 | 0.74 | KDM4E (0.58) | KDM4EKMT2AP2RX3ALDH1A1HTT | |
| SCHEMBL29388363 | 0.74 | KDM4E (0.58) | KDM4EKMT2AP2RX3ALDH1A1HTT | |
| SCHEMBL14575607 | 0.74 | KDM4E (0.44) | KDM4EKMT2AP2RX3ALDH1A1PDE10A | |
| SCHEMBL11625312 | 0.74 | KDM4E (0.42) | KDM4EKMT2AP2RX3ALDH1A1PDE10A | |
| SCHEMBL3448876 | 0.73 | KDM4E (0.37) | KDM4EKMT2AALDH1A1HTTTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |