Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.74 |
| ▸ | S1PR5 | Q9H228 | 11/20 | 0.74 |
| ▸ | GRK5 | P34947 | 1/20 | 0.58 |
| ▸ | CDK8 | P49336 | 1/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027737 | 0.86 | S1PR5 (1.00) | S1PR1S1PR5GRK5CDK8S1PR3 | |
| SCHEMBL31395248 | 0.81 | HIF1A (0.58) | S1PR1S1PR5S1PR3S1PR4ALDH1A1 | |
| SCHEMBL21061654 | 0.80 | ALDH1A1 (0.65) | S1PR1S1PR5S1PR3S1PR4ALDH1A1 | |
| SCHEMBL565212 | 0.80 | S1PR5 (0.87) | S1PR1S1PR5GRK5CDK8S1PR3 | |
| SCHEMBL51920 | 0.77 | S1PR5 (0.81) | S1PR1S1PR5GRK5CDK8S1PR3 | |
| SCHEMBL3042076 | 0.74 | S1PR1 (0.77) | S1PR1S1PR5S1PR3S1PR4 | |
| SCHEMBL3713589 | 0.74 | S1PR5 (0.76) | S1PR1S1PR5S1PR3S1PR4SIGMAR1 | |
| SCHEMBL16695243 | 0.74 | S1PR5 (0.82) | S1PR1S1PR5S1PR3S1PR4SIGMAR1 | |
| SCHEMBL5639896 | 0.74 | S1PR5 (0.76) | S1PR1S1PR5ALDH1A1SIGMAR1 | |
| SCHEMBL3043545 | 0.73 | S1PR1 (1.00) | S1PR1S1PR5GRK5CDK8S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049767-A1 | AMIDE PRODRUGS AND USES THEREOF | AUTOBAHN THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |