Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.47 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31395483 | 0.94 | BRD4 (0.54) | BRD4 | |
| SCHEMBL31395287 | 0.89 | BRD4 (0.45) | BRD4EEDMEN1KMT2A | |
| SCHEMBL31395339 | 0.83 | BRD4 (0.54) | BRD4 | |
| SCHEMBL31395392 | 0.82 | BRD4 (0.53) | BRD4MEN1KMT2A | |
| SCHEMBL31395418 | 0.82 | BRD4 (0.46) | BRD4EEDMEN1KMT2A | |
| SCHEMBL31395475 | 0.81 | BRD4 (0.45) | BRD4KMT2A | |
| SCHEMBL31395489 | 0.79 | BRD4 (0.59) | BRD4 | |
| SCHEMBL31395468 | 0.78 | BRD4 (0.52) | BRD4 | |
| SCHEMBL15067765 | 0.77 | BRD4 (0.62) | BRD4 | |
| SCHEMBL17492642 | 0.77 | BRD4 (0.53) | BRD4EEDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739307-A2 | TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY | The General Hospital Corporation (US) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025010291-A2 | TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY | THE GENERAL HOSPITAL CORPORATION (US) | 2025-01-09 | — | — | WO | disclosed |