SCHEMBL31395483

SCHEMBL31395483

Cc1ccc(S(=O)(=O)n2ccc3c(-c4cc(F)cnc4Oc4ccc(F)cc4)cn(C)c(=O)c32)cc1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31395367 0.94 BRD4 (0.47) BRD4
SCHEMBL31395339 0.89 BRD4 (0.54) BRD4
SCHEMBL31395392 0.89 BRD4 (0.53) BRD4
SCHEMBL31395489 0.85 BRD4 (0.59) BRD4
SCHEMBL31395468 0.84 BRD4 (0.52) BRD4
SCHEMBL15067765 0.83 BRD4 (0.62) BRD4
SCHEMBL17492642 0.83 BRD4 (0.53) BRD4
SCHEMBL31395287 0.83 BRD4 (0.45) BRD4
SCHEMBL31395619 0.83 BRD4 (0.53) BRD4
SCHEMBL31395699 0.82 BRD4 (0.56) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739307-A2 TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY The General Hospital Corporation (US) 2026-05-13 — — EP disclosed
WO-2025010291-A2 TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY THE GENERAL HOSPITAL CORPORATION (US) 2025-01-09 — — WO disclosed
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