Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.36 |
| ▸ | MOGAT2 | Q3SYC2 | 3/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 5/20 | 0.35 |
| ▸ | MERTK | Q12866 | 5/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 4/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280414 | 0.89 | PTPN11 (0.43) | PTPN11CYP2D6TNIKCD274AXL | |
| SCHEMBL31396526 | 0.88 | PTPN11 (0.41) | PTPN11CYP2D6MOGAT2CD274HTR6 | |
| SCHEMBL30280401 | 0.85 | PTPN11 (0.45) | PTPN11CYP2D6CD274HTR6MAOA | |
| SCHEMBL31396521 | 0.82 | PTPN11 (0.50) | PTPN11AXLMERTKHTR6FLT3 | |
| SCHEMBL30280396 | 0.81 | PTPN11 (0.44) | PTPN11AXLMERTKHTR6FLT3 | |
| SCHEMBL30280390 | 0.80 | PTPN11 (0.42) | PTPN11MOGAT2AXLMERTKHTR6 | |
| SCHEMBL30280456 | 0.80 | PTPN11 (0.48) | PTPN11AXLMERTKHTR6MAOA | |
| SCHEMBL31396485 | 0.79 | PTPN11 (0.48) | PTPN11TNIKAXLMERTKHTR6 | |
| SCHEMBL31396613 | 0.79 | PTPN11 (0.48) | PTPN11AXLMERTKHTR6FLT3 | |
| SCHEMBL30280469 | 0.79 | PTPN11 (0.45) | PTPN11CD274HTR6MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425499-A1 | TYRO3 INHIBITORS | HALIA THERAPEUTICS INC (US) | 2024-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425499-A1 | TYRO3 INHIBITORS | TYRO3, TYR, TH | PTPN11 80/4885CYP2D6 1813/4885PRMT5 1815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.