Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396477 | 0.90 | PTGDR2 (0.35) | PTGDR2ENPP3ENPP1MAPTCYP3A4 | |
| SCHEMBL31396595 | 0.89 | PTGDR2 (0.33) | PTGDR2ENPP3ENPP1 | |
| SCHEMBL31396633 | 0.88 | ENPP3 (0.34) | PTGDR2ENPP3ENPP1MAPTCYP3A4 | |
| SCHEMBL31396494 | 0.88 | MAPT (0.37) | PTGDR2ENPP3ENPP1MAPTCYP3A4 | |
| SCHEMBL30280408 | 0.80 | ENPP3 (0.38) | PTGDR2ENPP3ENPP1MAPTLMNA | |
| SCHEMBL31396603 | 0.79 | MAPT (0.36) | PTGDR2ENPP3ENPP1MAPTCYP3A4 | |
| SCHEMBL31396543 | 0.79 | PTGDR2 (0.34) | PTGDR2ENPP3ENPP1MAPTLMNA | |
| SCHEMBL31396578 | 0.77 | PTGDR2 (0.37) | PTGDR2ENPP3ENPP1MAPTCYP3A4 | |
| SCHEMBL31436003 | 0.76 | MAPT (0.39) | PTGDR2MAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL31396602 | 0.75 | KCNH2 (0.36) | PTGDR2ENPP3ENPP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425499-A1 | TYRO3 INHIBITORS | HALIA THERAPEUTICS INC (US) | 2024-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425499-A1 | TYRO3 INHIBITORS | TYRO3, TYR, TH | PTGDR2 2791/4885ENPP3 1096/4885ENPP1 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.